Compounded SemaglutideCompounded Tirzepatide

Personalized GLP-1 Treatments

A personalized weight loss plan built around you

Compounded Semaglutide

$150/mo

Compounded Tirzepatide

$199/mo

Get started

Prescription required. Treatment is only provided if clinically appropriate, as determined by a licensed provider. Compounded medications are not FDA-approved. Results may vary.

  • Same price at every dose. No long-term contracts.
  • Free expedited shipping, discreetly packaged.
  • Physician-led protocol personalized to your goals.
  • Ongoing follow-up consultations and dose adjustments.

Common questions

Everything you need is taken care of. After submitting your health profile, a licensed medical provider will personally review your intake and build a treatment plan around your specific goals. If medication is appropriate, your provider creates a custom dosing schedule and your treatment ships directly to your door through a certified, state-licensed pharmacy.

You'll also have access to unlimited messaging with your dedicated care team, 24/7 — here for every question, adjustment, or concern along the way.

Trufa offers several clinically proven options depending on your health profile and goals. Our most popular weight loss treatments are compounded Semaglutide and Tirzepatide — both GLP-1 receptor agonists shown to reduce appetite and support meaningful, sustained weight loss.

For members looking beyond weight loss, we also offer Sermorelin for muscle support and recovery, and NAD+ for cellular energy and longevity. Your provider will recommend what's right for you after reviewing your full health history.

No problem at all — there are no cancellation fees and no long-term commitments. You can cancel your plan anytime directly through your online patient portal in just a few clicks.

One thing to keep in mind: canceling your plan won't automatically stop any orders already sent to the pharmacy. If you have a pending order you'd like to pause, reach out to our care team directly and we'll take care of it right away.

Compounded in the U.S.A.FSA & HSA Eligible

Your path to results, start to finish.

From your first question to your first dose — here's exactly what to expect.

Complete your intake and connect with a physician

STEP 1

Complete your intake and connect with a physician

Fill out a short health questionnaire online. A licensed U.S. medical provider personally reviews your profile and determines whether treatment is right for you — 100% online, no in-person visit required.

Free delivery, straight to your home

STEP 2

Free delivery, straight to your home

If you're a good candidate, your provider issues a prescription and your custom treatment ships from a certified compounding pharmacy straight to your door — fast, free, and discreetly packaged.

Stay supported every step of the way

STEP 3

Stay supported every step of the way

Your care doesn't stop at delivery. Your Trufa team is available around the clock for check-ins, dose adjustments, and any questions that come up — so you're never navigating this alone.

Your journey

What to expect, week by week.

1
Day 1

Your protocol begins

Complete a short intake form. A licensed physician reviews your profile and issues a prescription — typically within 24 hours.

2
Week 1

Medication at your door

Your compound ships within 24–48 hours, discreetly packaged with full dosing instructions and a support contact.

3
Week 4

Appetite starts to shift

Most patients notice significantly reduced hunger and fewer cravings. Early weight changes begin to appear.

4
Week 12

Visible progress

Clinical trials show an average of 5–8% body weight reduction at this stage. Energy and confidence follow.

5
Month 6

Real transformation

Semaglutide patients average 10–15% body weight loss. Tirzepatide patients average 15–20% — life-changing for most.

Real results

People who chose to start.

Before and afterMonth 0Month 18

"For the first time in 16 years I stepped on the scale and saw under 200 lbs. A year and a half ago I was almost 330. Back then, getting out of bed was a challenge. Now I walk everywhere because I actually enjoy it. I've gotten parts of myself back I thought were gone forever."

Verified GLP-1 User

−127 lbs
BeforeMonth 0
AfterMonth 3

"I'm just in shock with how much has changed. I haven't felt this great physically, mentally, and emotionally in years. After 3 pregnancies I just couldn't get the weight moving — I'm so thankful I finally decided to do something for myself."

Verified GLP-1 User

−23 lbs
Before and afterMonth 0Month 2

"When I started, 4 shots in and now 8 shots in — so freaking happy and glad I took pics along the way. Body dysmorphia is real. You look in the mirror and wonder if anything's changed. The photos don't lie. If you're thinking about it, DO IT."

Verified GLP-1 User

−20 lbs

Going deeper

A few more things worth knowing.

Compounded medications are custom-prepared by licensed, state-regulated pharmacies — meaning your treatment is mixed specifically for you based on the dose and formulation your provider prescribes. Unlike mass-produced drugs, compounded versions aren't FDA-approved as finished products, but the active ingredients and facilities are held to strict regulatory standards.

This allows your provider to fine-tune your starting dose, titration schedule, and formulation in ways that off-the-shelf options simply don't allow.

Your provider monitors your progress throughout treatment and can adjust your protocol at any time. If your current dose isn't delivering the results you're working toward, they can modify your dosing schedule, switch you between Semaglutide and Tirzepatide, or explore other adjustments to better suit your body's response.

You're never locked into a dose — the plan is designed to evolve with you.

Most weight loss methods work against your body — requiring constant restriction or willpower. GLP-1 receptor agonists work with your biology by directly targeting the hormonal signals that control hunger, fullness, and metabolism.

Unlike stimulants or appetite suppressants that wear off quickly, GLP-1 treatments produce gradual, sustained results with clinical trials showing average weight reductions of 15–21% of body weight — a level of efficacy no diet or lifestyle intervention alone has matched at scale.

Not necessarily. Many patients with conditions like type 2 diabetes, hypertension, or high cholesterol actually see additional benefits from GLP-1 therapy beyond weight loss. Your provider will review your full health history during intake to determine what's safe and appropriate for you specifically.

Certain conditions or medications may affect your eligibility, which is exactly why a licensed provider review — not an algorithm — is part of every Trufa intake.

There's no minimum time requirement and no contracts. That said, GLP-1 therapy is most effective when given time to work — most patients begin seeing meaningful changes by weeks 8–12, with the most significant results appearing between months 3 and 6.

Some members choose to taper off after reaching their goal weight, while others continue at a maintenance dose. Your provider will help you think through a plan that makes sense for where you are.

Trufa

Physician-guided care for weight, longevity, and cellular health. 18+, U.S. residents only.

This website does not provide medical advice. Prescription products require an online consultation with a licensed provider who determines whether treatment is appropriate. Not everyone is eligible. Do not use GLP-1 medications if you have a personal or family history of medullary thyroid carcinoma (MTC) or MEN2. Compounded medications are not reviewed or approved by the FDA. Results vary and are not guaranteed. Research peptides are intended for laboratory research purposes only and are not for human consumption unless prescribed. © 2026 Trufa Health. All rights reserved.